A Focus on the Challenges with Utilizing Remote Monitoring in Patient Healthcare

Mar 28, 2023 | News |


Remote patient monitoring (RPM) technology allows healthcare providers to monitor patients without requiring them to be physically present in a healthcare facility. The potential use of remote monitoring technologies in patient health is endless in various clinical settings and healthcare applications, including post-operative care, mental health treatment, trials for new drugs and medical devices, as well as in the management of chronic diseases.

Main Point

Remote patient monitoring methodology uses technology to remotely track patient health status, behavior, and adherence to the prescribed treatments. Healthcare professionals, researchers, and clinical trial sponsors must ensure that the RPM system complies with all applicable laws and regulations, including those related to data security and privacy, patient consent, and device certification, while also addressing ethical concerns related to the use of RPM systems, such as patient autonomy and privacy. [1,3,8] This paper provides an informative synopsis on the challenges and solutions use of utilizing remote monitoring technology in clinical setting.

Utilization of RPM

What are the challenges and solutions of utilizing remote patient monitoring technology in clinical trials?

  • Challenge: Patients, especially the elderly population, have limited technological literacy and have problems using the technology correctly and consistently.
    • Solution: To provide adequate training and support to patients to ensure that they can use the RPM technology effectively. For example, some RPM systems provide patients with user-friendly interfaces and easy-to-understand instructions, while others offer training and support through webinars, videos, or live chat. [2 – 4]
  • Challenge: Ensuring data quality and accuracy (i.e., patients' vital signs and other health metrics, etc.).
    • Solution: RPM systems must be properly calibrated and regularly checked for accuracy. Additionally, clinical trial teams must develop clear guidelines for patient data collection and management to ensure that the data collected is reliable and consistent across all patients. This data should be collected automatically and objectively, thus reducing the potential for human error or bias and ultimately lead to more reliable and accurate results. [3, 6, 7, 10]
  • Challenge: Ensuring data privacy/security, minimizing data breach, protecting data storage/transmission to research sites.
    • Solution: To address this challenge, RPM systems should be designed with robust security features, such as encryption and access controls, and research sites and data management systems should have adequate security measures in place to protect patient data. [5, 9]
  • Challenge: Ensuring patients can use RPM systems effectively, particularly those who are older or have limited digital literacy.
    • Solution: This challenge can be addressed by providing clear and concise instructions on how to use RPM devices, offering training and support, and ensuring that devices are user-friendly and accessible. [3, 7, 10]
  • Challenge: An additional challenge associated with RPM systems is ensuring that the technology is compatible with existing healthcare infrastructure. This can be a challenge, especially for clinical trials conducted across multiple sites or countries, as different healthcare systems may have different technology requirements and standards.
    • Solution: To address this challenge, clinical trial teams must ensure that the RPM technology used is compatible and that it can be integrated into electronic health records (EHRs) seamlessly. [3] This can be achieved through close collaboration with healthcare providers and IT professionals. Despite these challenges, RPM systems offer numerous advantages in clinical trials, including improved patient interaction and study trial compliance , reduce dropout rates, reduced clinical trial costs, help identify potential adverse events earlier, and reducing the need for costly interventions and hospitalizations. [3-5]
  • Challenge: May not be suitable for all patients or all clinical trial scenarios. For example, patients with severe health conditions or those who require more intensive medical care may not be suitable for RPM . Additionally, certain types of clinical trials may require more frequent in-person visits or interventions, making the remote patient monitoring less feasible.
    • Solution: It is important to consider these factors when designing and implementing RPM systems that focuses on patient-centered design principle to ensure that RPM devices are user-friendly and accessible and tailored to meet their needs and preferences. [3, 4]


RPM technology is a promising approach for improving patient outcomes in clinical trials. RPM systems offer numerous benefits, including improved patient compliance, reduced costs, and earlier identification of adverse events. However, there are several challenges associated with implementing RPM technology, including limited patient technological literacy, data quality and accuracy, data privacy and security, compatibility with existing healthcare infrastructure, and suitability for all patients and clinical trial scenarios.

Although there are numerous concerns that must be addressed, such as the need for secure and reliable technology and effective communication between patients and healthcare providers, remote monitoring can be a beneficial tool  for researchers and healthcare providers seeking to improve patient health. It can also provide greater patient autonomy and convenience, as well as reduce overall cost of care. Additionally, it can be used to collect data from large numbers of patients simultaneously, making it an invaluable tool for clinical trials and research. To address these challenges, it is important to provide adequate training and support to patients, ensure data quality and accuracy through calibration and clear guidelines, prioritize data privacy and security through robust security features, ensure compatibility with existing healthcare infrastructure through collaboration with healthcare providers and IT professionals, and design RPM systems with patient-centered principles.

Overall, RPM technology has the potential to revolutionize clinical trials by improving patient outcomes and reducing costs. As technology continues to advance and healthcare providers become more familiar with RPM systems, we can expect to see more widespread adoption of this technology in clinical trials and beyond. By addressing the challenges associated with RPM technology and continuing to prioritize patient-centered design principles, we can ensure that RPM technology is used effectively and ethically to improve patient outcomes and advance medical research.

Evita Asumugha – Senior Medical Writer


  1. Research C for DE and. Digital Health Technologies for Remote Data Acquisition in Clinical Investigations. U.S. Food and Drug Administration. Draft Published December 2021. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/digital-health-technologies-remote-data-acquisition-clinical-investigations
  2. Evans J, Papadopoulos A, Silvers CT, Charness N, Boot WR, Schlachta-Fairchild L, Crump C, Martinez M, Ent CB. Remote Health Monitoring for Older Adults and Those with Heart Failure: Adherence and System Usability. Telemed J E Health. 2016 Jun;22(6):480-8. doi: 10.1089/tmj.2015.0140. Epub 2015 Nov 5. PMID: 26540369; PMCID: PMC4892222.
  3. How Remote Patient Monitoring Technology Can Impact Decentralized Clinical Trials. Applied Clinical Trials Online. https://www.appliedclinicaltrialsonline.com/view/how-remote-patient-monitoring-technology-can-impact-decentralized-clinical-trials. Published September 16, 2022. Accessed September 29, 2022.
  4. Manyam H, Burri H, Casado-Arroyo R, et al. Smartphone-based cardiac implantable electronic device remote monitoring: improved compliance and connectivity. European Heart Journal – Digital Health. 2022;4(1):43-52. doi:https://doi.org/10.1093/ehjdh/ztac071
  5. Health P. A Comprehensive Guide to Remote Patient Monitoring. www.prevounce.com. Published 2021. https://www.prevounce.com/a-comprehensive-guide-to-remote-patient-monitoring
  6. Halamka J. FDA Outlines Best Ways to Collect Remote Data for Clinical Trials. Mayo Clinic Platform. Published May 12, 2022. Accessed February 27, 2023. https://www.mayoclinicplatform.org/2022/05/12/fda-outlines-best-ways-to-collect-remote-data-for-clinical-trials/
  7. Remote Patient Monitoring -Now or Never. https://www.medtecheurope.org/wp-content/uploads/2022/04/remote-patient-monitoring-now-or-never.pdf
  8. Marra C, Gordon WJ, Stern AD. Use of connected digital products in clinical research following the COVID-19 pandemic: a comprehensive analysis of clinical trials. BMJ Open. 2021;11(6):e047341. doi:https://doi.org/10.1136/bmjopen-2020-047341
  9. How to Mitigate the Risks of Remote Patient Monitoring. The Doctor Weighs In. Published December 7, 2018. https://thedoctorweighsin.com/remote-patient-monitoring-risks/
  10. Digital Health Technologies for Remote Data Acquisition in Clinical Investigations Guidance for Industry, Investigators, and Other Stakeholders Draft Guidance. https://www.fda.gov/media/155022/download